In my clinic, two of the most powerful treatments now commonly used for children on the autistic spectrum were discovered by accident – methylcobalamin (methyl-B12) and hyperbaric oxygen therapy. My presentation focuses on the use of oxygen under pressure as a powerful treatment modality for children on the spectrum. Interestingly, for children with autism, there appears to be a synergistic effect between the two. In my practice approximately 80% of children respond to HBOT to some degree, especially if they continue their treatments, and probably because they are also being treated with methyl-B12. I have found that HBOT is a treatment, not a cure and that continued treatment sets of sessions actually build upon any previous treatment sets of sessions therefore providing a cumulative beneficial effect, much like the educational process builds upon what was learned in the past in order to learn even more for the future.